Post # 1
I had a doctor’s appointment this afternoon and she prescribed me Metformin to help boost ovulation in the hopes of DH and I getting pregnant.
Some backstory: I was diagnosed with PCOS in the Spring of 2015. However, I have had issues long before that. I have hypothyroidism that has progressed to Hashimoto’s. I gained about seventy pounds once the PCOS symptoms started to really ramp up, but have lost about 25 of those with the hope of losing more throughout the year. DH and I stopped using birth control soon after my diagnosis as we knew it could take us a long time to get pregnant. Since then, we haven’t even had a scare. I have gotten my thyroid levels under control to where my doctor is confident it wouldn’t be a hinderence. My cycles are incredibly heavy and irregular. They can last anywhere from four months to four days, a two day break, four days, etc. Due to this, getting pregnant has just not been an option. We have been “trying” for almost two straight years with no results (though we aren’t surprised by this due to my irregular cycles).
So, for any other ladies who have PCOS . . . what has your experience been with Metformin? Did you get pregnant? How long were you on it for before getting a BFP?
I have been prescribed a dose of 500 twice a day with the idea being that I increase it to 4 doses at 500 a day.
Post # 2
I took it for 6 months and got my bfp after a year of trying without it. It also helped me lose weight and I would got back on it immediately if I were to try for baby #2. I had no bad side effects.
Post # 3
My cycles were awful before I went on the pill in my mid twenties. I’d get a period maybe every six months, and they were super heavy and crampy. I was diagnosed with PCOS but wasn’t TTC so I just went on the pill. In my early thirties, I got married and went to an endocrinologist who put me on Metformin for six months before I stopped taking birth control. Immediately after stopping the pill, my cycles regulated and I got pregnant on our first try. I miscarried that pregnancy, then it took six months of trying to get pregnant again, but that pregnancy ended with a healthy baby. I went back on metformin after giving birth and I’m currently pregnant with #2, which took 4 cycles of not really trying but not preventing and two cycles of actively trying.
Wishing you lots of great luck!
Post # 4
I have PCOS as well and was only having a period 2-3 times a year. I started Metformin in January 2014. I did 500mg for a week then up to 1000mg for another week then settled on 1500mg. Lots of people don’t see any results before that dose. I lost about 20lbs on it in 2 months and had a natural period in March where I did ovulate but it was a weak ovulation. I induced a period using Provera and did Femara to induce a good ovulation in April and got pregnant. I unfortunately miscarried but did it again in August and got pregnant with my son. So twice in one year after years of nothing. However that was a combo of Metformin and Femara. Talk to your doctor about Femara or Clomid. We also used a special lube for TTC called conceive plus and I would put in a soft cup immediately afterwards to help keep everything in there and of course tracked ovulation with OPKs. Feel free to message me if you ever need any help. I’ve been there and it can be overwhelming. I’ll be doing it all again in a few months for #2.
Post # 5
In my early 20’s when I reached my highest weight ever (306lbs at 5’7″) my cycle started getting all messed up and i missed like 3 periods in a row.. and my family doctor said I was pre-diabetic (i was developing insulin resistance, I did the 2 hr sugar in test… and i was not too bad but borderline) and my gyno though I may have PCOS but had no other symptoms other than the very long cycle/absence of menstruation for 90 days.. so both doctors recommended to try Metformin first to see if my insuling resistance and obesity was messing uo the rest of the hormones (I dont remember the frequency/dosage, I remember i started a lower dosage for the first couple weeks and then increased and stayed at that dose for 3 months I think, maybe 6, I dont remember. The first month I had an upset stomach (diarrhea almost every BM sorry for the TMI) but then it got better and my period returned and I lost a bit of weight.. went of the Metformin and my period was pretty good, not perfect but withing normal parameters, years later I went on the pill at 25 (Alesse, actually Alesena, the generic version of Alesse) and was on it for 3 years and last spring I decided I’ve had enough crazy moods.. and now we just use condoms , and I chart. And my cycle is 28-30 days. We arent TTC yet, probably not till next spring but I just wanted to chime in since I did take Metformin and it helped my cycle and Im assuming it would have helped if I was TTC at the time.
Post # 6
emeraldgrey : I am going to see my gyno in May and when I saw him last August our assumption was if it hadn’t happened naturally, we would start Clomid. My endo knew this as well, so she prescribed the Metformin so I’d already be worked up to a high enough dose by the time we started Clomid to, hopefully, have quick results. It has definitely just been a little…draining is a good word. Just knowing that it wasn’t going to happen regardless of what we did naturally kind of stinks.
KatieBklyn : Thank you for sharing! I am also kind of excited to just have a normal cycle for once in my life (it’s never been regular since I started my period at twelve).
happybunny : Thank you for sharing! I’m glad you had success with it!
ana2017 : Thanks for sharing!
Post # 8
I have PCOS and hypo (which my dr thought could be hashimotos as well) but my periods are different then yours (prior to metformin). Mine were always light and would skip months. I started metformin 2000 in October 2015 and didnt regulate my period until Dec/Jan and then I had a pretty consistant period with ovulation each month. We werent trying until after we got married in October 2016 and got pregnant in December 2016 due in August. So metformin definitely helped me get my cycle and start ovulating. There’s hope! It takes a while to get used it, and will mess up you stomach some but it’s worth it and even helps with wieght. I too gained about 50 pounds prior to being diagnosed with PCOS and with metformin i lost 30 lbs. Good luck!
ETA if it helps, I’m on 150 synthriod as well
Post # 9
I am on the low end of the PCOS spectrum, and I have the lean PCOS version so my experiences may be different. I would naturally get periods every 55 days or so. I went on 1000 mg of metformin and got pregnant after 3 months. It ended up being a blighted ovum. The very next cycle I got pregnant again but had a missed miscarriage at 8 weeks. I had to wait 2 cycles before TTC again after that, but noticed that my cycles were consistently getting more and more regular due to the metformin. This first cycle back to TTC, I did a combo cycle with 50 mg of clomid and am 19 weeks pregnant. Good luck!
Post # 10
MrsMeowton : I was diagnosed with PCOS in 2012, but I’m not a typical PCOS profile (5’2, 112lbs). I was on 1000-1500 mg of metformin for several years before TTC, and, along with BC, it immediately helped give me regular periods (I didn’t have a period for 9 months , and was on BC, so needed both). Once we decided TTC for our daughter, we got pregnant our first time trying. We also got pregnant our first time trying for baby #2. I was still on metformin, but obviously not on BC. My cycles were still long (40-50 days), but with temping and OPKs I was able to get pregnant. If I wasn’t temping or OPKing, I’m guessing it would ahve taken me a lot longer (we conceived our daughter on CD 40). I really think the Metformin made ovulation, and TTC possible!
Post # 11
ddsbride : Thank you for sharing! My periods are awful. I would go six months without it, six months with it, etc. Very heavy and draining. I’m glad that it worked for you! I have read up on the stomach issues and I am very willing to have those side effects if it means I can finally get pregnant!
MrsMellyBean : Thank you for sharing and congrats on your pregnancy!
ADiamondInTheRough : Thank you for sharing! I am hoping that we can conceive without having to chart/temp because I just don’t think I’d be very good at it. I’ve looked into it and it makes me feel very overwhelmed haha. I’m so happy it worked out for you, though!
Post # 12
Hopefully metformin will help regulate you like it did me, and if you need a boost to make yourself ovulate the dr can always prescribe clomid. Baby dust!!
Post # 13
Oh by the way, if your prescription plan doesn’t make it prohibitively expensive, ask for Metformin XR. I found it’s much easier on the stomach/gastrointestinal system than the regular Metformin.
Post # 14
I have PCOS and started metformin in October of 2015 at 500mg/day. I had totally random periods that were super light. I took metformin for a few months and tried to track ovulation using OPK’s, but never got a positive. In February I took my first round of clomid and got nothing. March I took the second round and also increased metformin to 2000 mg/day, but this was about a week after I took the clomid. Kept taking OPK’s and finally got a positive (in my opinion it more lined up with the increase in metformin instead of the clomid). A week and a half later I took a pregnancy test and it was positive! On November 30th we welcomed our daughter. I definitely believe metformin can help in getting pregnant, I also stayed on it up until about 33 weeks pregnant- just at the lower 500 mg/day. Just a warning though, the higher amount you take the more it can reek havoc on your stomach- I had to take it every morning with a banana and oat square cereal (dry)- nothing else or I’d have to live by a bathroom for the first half of the day.
Post # 15
For me metformin is a love /hate thing. I’ve always had regular periods but have not been ovulating. Was diagnosed with PCOS in April 2016. We have been TTC since then.. my endo said that metformin did regulate my hormones …. So I just stopped taking it..And I ovulated for the first time. I’m in the tww now (3dpo) so we will see!