(Closed) Any MTHFR's out there?

posted 6 years ago in TTC
Post # 3
Member
2550 posts
Sugar bee
  • Wedding: July 2011

I don’t but several ladies on my other board discuss, resolve.org, infertility section. 

Post # 5
Member
1659 posts
Bumble bee
  • Wedding: July 2012

@dodgercpkl:  I’m resurrecting this because my doctor just called and my bloodwork came back MTHFR positive. I don’t know which and if it’s heterosexual or homo yet, but I’m looking forward to learning about treatment options.

I actually  didn’t have trouble conceiving (2 healthy pregnancies, no miscarriages) but I do have PMDD and a family history of reproductive issues on my mom’s side. My doctor tested me because of my history with ADHD, anxiety, and depression. I’m already taking a supplement, and I feel slighy different but I’m hoping the doctor has an idea for long-term treatment. He’s a naturopath and this is his website – mthfrcure.com. I go in next week, kind of excited πŸ™‚

Post # 7
Member
1659 posts
Bumble bee
  • Wedding: July 2012

@dodgercpkl:  LOL I wonder if my phone did that?  Ha! Definitely not testing for any homosexual genes πŸ™‚

I had my visit today – turns out I am homozygous, which I didn’t expect because we had almost no issue conceiving (first baby was unplanned, second was third cycle) and no miscarriages but there is a history of miscarriage and infertility on my mom’s side.  I’m also homo c677t. 

He’s going to have me ramp up to 10mg/day of methylfolate.  He said that a lot of his patients who present like I do (adhd, ocd, depression) feel best at 10mg.  He’s also concerned about my kids, because they’ll have at least one copy, so he wants to make sure I’m getting as much folate through nursing to the baby as possible and to make sure my older daugther isn’t getting any folic acid because it could interfere with the folate she is getting.

When I’m done nursing (a year…) he wants to test for heavy metals and do a detox.  This is all so fascinating, isn’t it?  I am sooooo happy that you tested as well, and I really hope that you are able to get the point where you can conceive a sticky healthy baby. I have a friend (actually referred me to this doctor) who is also homo positive and she and her husband were so distraught over not being able to conceive.  Testing and treating for MTHFR has really helped her to stop blaming herself for their inability to conceive and in a way I feel the same relief – there’s a genetic reason why I feel crazy, and I can treat without ODing on pharmaceuticals πŸ™‚

Post # 9
Member
4803 posts
Honey bee
  • Wedding: August 2012

I definitely opened this to find out what a “mother-effer” was and if I was one!  Well, now I know, but I don’t have any experience with it as far as I know.

Sorry for all of the difficulties you are going through.

Post # 11
Member
402 posts
Helper bee

I don’t know for sure if I’m an MTHFR, but it runs on my mom’s side of the family and several of my relatives have recently confirmed that they are. My primary care doctor keeps resisting when I ask to be tested (who knows why) but I’d really like to know. My female relatives who have it have all had multiple miscarriages, some 2nd trimester, and I’m getting ready to TTC within the next year – so it’s been on my mind. What’s devastating is that the women in my family get pregnant easily, and then have a very difficult time staying pregnant. I really hope I don’t face a TTC journey like theirs. 

Bipolar disorder runs on my mom’s side as well (I was diagnosed with it 5 years ago), and I wouldn’t be surprised if it’s linked to the MTHFR.

I take high-dose vitamin B complex supplements every day because I suspect I have a hard time absorbing them. Because I’m bipolar, I’m building a network of mental health professionals who are going to monitor me from before I even start TTC, and get me on a medication regimen that’s safe for pregnancy (it’s really not a good idea for me to be off meds completely). I’m hoping to find a primary care doc who is less flippant about the whole thing too.

Post # 13
Member
402 posts
Helper bee

@dodgercpkl:  THANK YOU! I’m going to look into 23andme and other forms of B Vitamins. I’ll let you know if I have any questions. πŸ™‚

Post # 15
Member
515 posts
Busy bee
  • Wedding: June 2012

I have mthfr! Im homozygous on c677t. Im currently taking NeevoDHA(pretnetal specifically for wome with the c677t mutation) it has L methylfolate calcium(metafolin) as well as b6 and b12 and other b vitamins ..it does not have folic acid(we cant process it, its pointless to take), also taking a baby aspirin.

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