Failed FET

posted 2 years ago in TTC
Post # 2
Member
2156 posts
Buzzing bee
  • Wedding: August 2014

I’ve never done a FET only fresh transfers. I’m very sorry to hear that it did not work. Unfortunately, it actually pretty common for IVF to fail the first time, but it doesn’t make it suck any less. Have you done an ERA? It is supposed to measure when in your cycle you are receptive for transfer.  Sometimes you need more or less progesterone prior to transfer to reach the ideal timing. I’d ask my Dr. about that before transferring again. 

As for transferring two, it actually does not greatly increase your chances of success, I think it increases it only 5-10%. Statistically, you are much better off transferring one at a time, thus giving you 3 chances at success given you are unable to do another retrieval. Generally, I’d only transfer 2 if they are both lower quality. Do you know what they are graded?

Post # 3
Member
467 posts
Helper bee

Im so sorry about your failed fet thats so hard. I hope you dont mind me following as I dont actually have any advice but am interested to see what advice anyone does have. 

I just had a failed fresh cycle…positive tests which faded  to negative after about a week. I had 4 eggs retrieved & all fertilised,  all good on day 3 but only 2 blasts. The other 2 were not suitable to freeze. I am going to transfer my 1 frostie as soon as I can,  I need to have 1 natural cycle first so probably some time in April. 

I have to say like you I thought we would have a good outcome,  we conceived naturally last year but lost baby & tube at 8 wks due to a ruptured ectopic so though we’d be good once we got it to the right spot. Trying to hold onto hope that we’ll get lucky on our fet. Im also 35. 

Post # 5
Member
2156 posts
Buzzing bee
  • Wedding: August 2014

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Dfitzy :  Unfortunately, the visual grading does not necessarily correleate to whether your embyro is abnormal. A perfect looking embryo can be abnormal and a visually poor quality embryo can be normal. I am not necessarily a fan of PGS testing but if you truly want to know the quality of the embryo, PGS testing is really the only way. That being said, there is still only 50-60% chance that a normal embryo will implant even in the best of scenarios. I don’t think the ERA is surgical in nature, it is more similar to an HSG so I’d definitely recommend asking your Dr. You could also suggest an endometrial scratch. I think they are generally done together (ERA and scratch). Good luck

Post # 6
Member
2180 posts
Buzzing bee

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Dfitzy :  I’m so sorry that embryo didn’t stick. There’s lots of reasons why an embryo won’t stick, even PGS normal ones. It’s not fun, but I’m hopeful your next one will take! No advice here, I’m just thinking about you and hopeful that you’ll be pregnant soon enough.

Post # 8
Member
2180 posts
Buzzing bee

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Dfitzy :  Can’t wait to hear how the next one goes! I think transferring one again is a good idea. The odds per embryo are actually higher on single transfer! Glad you have a plan and I hope the next few weeks off can be restful.

Post # 9
Member
3877 posts
Honey bee
  • Wedding: October 2013

My first transfer failed! We did a fresh transfer that resulted in a chemical pregnancy (I only knew I was pregnant because I tested early, but by the time I did my beta my numbers were 0). We were also MFI and also did not do genetic testing for the same reasons as you. I think it was just an abnormal embryo (20% of them are abnormal, naturally). My doctor said he was super surprised it didn’t work. We did an FET soon after and that one stuck! I know it is extremely disappointing, but don’t get discouraged! And transferring 2 doesn’t increase your chance of pregnancy per se, but does increase your chance of multiples for sure which is high risk. I would try transferring just one again.  Best of luck with the next one! Fingers crossed for you. 

Post # 10
Member
1144 posts
Bumble bee
  • Wedding: October 2013

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Dfitzy :  I am sorry that is really hard when it doesnt work! I really hope your embryo sticks next time! I think transfering one sounds like a good idea and like others have said the grading doesnt tell you if its genetically normal. Also even pgs notmal embryos may not implant. I did a fresh transfer that resulted in a  miscarrage and it was a 5AB embryo. I did a fet that was a 5BB and it resulted in my daughter. Your doctor is probably right and   the first one you transferred probably was just not genetically normal. I was like you and wanted to stick 2 in the next time but my doc talked me out of it as she said if one embryos miscarries it can actually cause the other healthy embryo to miscarry too. Not always but I didnt want to chance it. Im sure your doctor will advise you correctly. I think you have a good shot of the next one sticking! Good luck!!!

Post # 12
Member
127 posts
Blushing bee
  • Wedding: October 2017 - Santa Margarita Ranch

I’m so sorry that it didn’t work out for you this past cycle. I’ve never done an FET, so I can’t imagine how hard it must be.

ITA with larissaka though…I used to work as a surrogacy case manager and I can’t tell you how many times a perfectly healthy PGS tested embryo was transferred into a surrogate and it didn’t stick on the first try. It’s almost harder to wrap your head around in that scenario, so I’m glad your RE got back to you so quickly and thinks it was an abnormal embryo. So many times on the second the embryo did finally stick and it turned into a super healthy normal pregnancy.

Hang in there and lots of <3 !

Post # 14
Member
609 posts
Busy bee
  • Wedding: August 2016

So sorry to hear this but best of luck for April, I understand it must be so hard to go through all of that and it not to work. I’ve not had ivf yet I’m waiting.

If it makes you feel any better I understand that it’s common to need 2-3 cycles to get pregnant. Where I’m from we are very lucky to get funded treatment and they fund 3 cycles as it will not be uncommon for cycle 1 not to work but then cycle 2 or 3 will. This is based on extensive fertility research and they would not fund 3 cycles if number 2 or 3 were very likely to fail. So the next cycle could well be successful for you, I have my fingers crossed. 

Take care of yourself, hope you are getting support.

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