Has anyone ever had multiple mc's with no explanation?

posted 3 years ago in TTC
Post # 2
Member
1012 posts
Bumble bee

I’m CFBC, but both my mother and my older sister had multiple MCs in their quest to have children. My mom had my older sister, and then had 2 MCs before having me (one was late term). She then went on to have me, and my younger sister.

My older sister had two MCs before having my niece and my nephew. 

They have no explanation, but are both grateful that they ended up being able to have healthy children. They do have theories and such, but nothing ever identified by a doctor. 

Post # 3
Member
2627 posts
Sugar bee
  • Wedding: April 2017 - Hogarths, Solihull

Sunshine09 :  Future Mother-In-Law had a few MCs before and after having Fiance. He’s an only child and he was 4 weeks premature as it was.

There was no medical explanation, but she does know that at least one of the lost babies was a girl. She wonders whether maybe she just couldn’t carry girls for some reason.

My Mum also had a MC before she had me. She has a suspicion for it, but there’s no medical reasoning to suggest that she is correct.

Post # 4
Member
831 posts
Busy bee
  • Wedding: December 2013

Sunshine09 :  My first two pregnancies ended in MC. I am currently 34 weeks pregnant now. None of the tests the doctors did came up with anything besides “bad luck.”

Post # 5
Member
14947 posts
Honey Beekeeper
  • Wedding: June 2011

I’ve had 2 back to back now, second one with a PGS tested normal embryo with no explaintion.  I’ve done the immunity and blood clotting blood workup, all other bloods are normal too.  Our next test is the Yale EFT test to see if that uncovers anything.

Post # 6
Member
9434 posts
Buzzing Beekeeper
  • Wedding: August 2012

Have you had additional testing done? How many losses have you had?

I took lovenox for a blood clotting disorder during my pregnancy, but I know sometimes doctors will prescribe it as a “we don’t know exactly what’s wrong but this might help” type of thing. For some reason it seems to help some people.

Post # 8
Member
2419 posts
Buzzing bee
  • Wedding: April 2014

I’ve had two early MC, one just after 4 weeks and the other at 6w. We also had an IVF cycle with failure to implant. All of my RPL, blood clotting and DNA karyotying came back normal, so our losses are unexplained. It was originally thought that it was embryo quality – my RE said that the odds of having a second MC were 40%. But since then, we are starting to think it is a blood flow/lining issue with my uterus. We are still working on achieving a pregnancy/live birth. Best of luck to you!

Post # 9
Member
1161 posts
Bumble bee

Sunshine09 :  my mum’s friend had a lot of MCs after her 1st two kids. turned out it was because she was gluten intolerant and once she cut it out she went on to have 2 successful pregnancies. 

Post # 10
Member
234 posts
Helper bee

I had two miscarriages and had blood clot testing done which came back negative. My miscarriages were also not related to chromosome issues. After my second miscarriage we were taking a break from trying and I got pregnant and I am now due in 5-6 weeks. 

My two miscarriages were very different from each other and my doc kept saying it was bad luck. When I got pregnant the third time I did request to have my progesterone tested and it was a little low so I started supplements around 4 weeks. I don’t know if that made a difference or not with this pregnancy being successful, but it definitely gave me some peace of mind.

best of luck to you and PM if you ever want to talk more. I know how hard it is!

Post # 11
Member
145 posts
Blushing bee

Have you guys been tested for MTHFR?

Post # 12
Member
950 posts
Busy bee
  • Wedding: December 2014

I had 4 losses before 7 weeks and then one 9 week loss. No real explanation why, one we know was chromosonal but no reason why we would have such bad luck as I was in late 20s, healthy and all tests were good. Tried again on the same medication and i’m now 31 weeks pregnant. We did try so many things so hard to know if anything actually worked but we never had a clear medical answer for anything. I did try dietary changes eg gluten free, acupuncture, hysteroscopy, laparoscopy, aspirin, lovenox, profesterone, prednisone. However we tried a lot of those meds in the previous pregnancies and failed too so I think this baby is just a fighter!

Post # 13
Member
2787 posts
Sugar bee
  • Wedding: June 2011

I had 7 losses before I had my son, 6 chemical pregnancies and 1 miscarriage (genetically normal embryo tested after D&C). My RE never found a reason for my losses but she thought it could be due to my Diminished Ovarian Reserve (low number of eggs) and that in my case it also meant I had a bad egg quality. After having my son, I got pregnant again on my second cycle post partum and so far it seems to be a healthy pregnancy (17 weeks).

Post # 15
Member
5161 posts
Bee Keeper
  • Wedding: January 2010

Sunshine09 :  Not my personal story, but my maternal grandmother had over 10 miscarriages before having 5 live, healthy births (she did have a couple more miscarriages in between pregnancies), and my mother had 7 miscarriages in the five years between having me (unplanned) and my brother (who was planned). My mother had a total of 3 live, healthy births…my sister was also unplanned but she had no miscarriages between my brother and her. Both my grandmother and mother’s miscarriages included in the 2nd and 3rd trimester, too.

Neither of them ever knew “why” it was happening, and I think they too were just told “bad luck”. My grandmother’s pregnancies were in the 1950s and 1960s, so it was also not something talked about much or looked into much back then either. 

When I was undergoing genetic testing for something else, the genetic counselor told me that it was possible a genetic mutation at play in my grandmother and mother’s miscarriages (like a MTHFR mutation) and it was something to look at in the future, but as I am CFBC I never explored it any further than that. 

 

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