(Closed) Issues with ovulation after trigger (ovidrel) shot?

posted 6 years ago in TTC
Post # 2
2051 posts
Buzzing bee
  • Wedding: May 2013

I’ve done 3 clomid+ovidrel+iui cycles so far, and on all 3 I’ve gotten noticeably EWCM or watery CM around 5 or 6 DP IUI, as well as cramping.  I think it’s a side effect of the ovidrel.  Clomid is notorious for drying up CM, so that’s probably why you didn’t have any around the time of the trigger shot.  I usually triggered when I had a follie around 20mm, which you probably had when you took your trigger shot (follicles grow 2-3mms a day).  I never checked my CP though, so can’t add any help there!

FX this cycle works for you!

Post # 3
9579 posts
Buzzing Beekeeper
  • Wedding: October 2013

do you temp?  i don’t and I took RE’s word that i O’d 36 hours after trigger.  DH and I still BDed the next 2 days just to make sure.

also, my RE’s office prescribed progesterone supplements that i would take twice a day starting the day after IUI regardless of what my progesterone level was.  i took the progesterone until my bloodtest.  unfortunately it was negative, so i stopped the pills and AF came 3 days later. 

Post # 6
2363 posts
Buzzing bee
  • Wedding: October 2012

View original reply
whitums:  I’m so sorry that your instincts were correct and you didn’t ovulate.    I would be devastated, too.  Big hugs!

I haven’t done the trigger yet (planning to next cycle), so I don’t have any advice for you.  How is your RE planning to proceed?


Post # 8
2 posts

I dont know if this post is still active but I had the same thing too. Probably one of the 5% that Ovidrel doesn’t work for. I also had three mature follicles 20, 18 and 15mm and I didn’t ovulate. I started getting scared when day 14 bloodwork was negative and no period. As I type this I am Day 55 of my cycle and no period. I am on Day 6 of my Provera though and hope something shows up. This was my first IUI cycle and the doc wants to do 2 more before we move to ivf. I am in my late twenties so he says I’m still young but I’m just confused as to why I would not ovulate with clomid and trigger shot of a monitored cycle. I have learnt not to feel anything again, the funny thing is I used to have regular periods till I started fertility treatments so I don’t know if I should just let it breathe and keep trying. On the other hand, I want to feel like I’m doing something but I am stuck. DH and I have unexplained infertility, we just clocked the one year mark of trying. 

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