(Closed) IVF Buddy Thread

posted 3 years ago in TTC
Post # 482
Member
1129 posts
Bumble bee
  • Wedding: July 2013

vanike :  yes I know what it means. 

Post # 483
Member
1129 posts
Bumble bee
  • Wedding: July 2013

vanike :  what I was saying is, they mentioned that on my form rather than ‘egg quality’ which seemed to be their concern due to my fsh. 

Post # 484
Member
2420 posts
Buzzing bee
  • Wedding: April 2014

YogaMama :  There isn’t a test for egg quality – FSH is one of a few indicators of egg quantity. Realistically, your AMH and AFC have to also be low to indicate poor ovarian reserve (DOR). FSH gives the RE an idea of how you will respond to medication and often your IVF stim protocol is based on this (so, the amount of meopur or repronex you will be on).

Egg quality can only be determined when you remove eggs from your body and observe them – are the atretic, do they fertilize, do they arrest early on after fertilization? Because you stated that you had normal AFC and AMH levels, your primary reason for infertility is likely “secondary” as you’ve been pregnant…which is all I think @vanike was trying to say!

Post # 485
Member
1129 posts
Bumble bee
  • Wedding: July 2013

BeverlyGeese :  sure, I get that- but secondary isn’t really a diagnosis is it? My doctor thinks I have lots of eggs but there could be a quality issue. Just hope they are keeping that in mind going forward with treatment 🙂

Post # 486
Member
2420 posts
Buzzing bee
  • Wedding: April 2014

YogaMama :  It absolutely is a diagnosis. Just like “unexplained infertility” is a diagnosis (albeit with no exact reasoning other than the inability to achieve pregnancy after 12 months, or 6 months if over 35 years old). Most of the time, secondary infertility also comes with additional problems that were a result of a former pregnancy: reduced egg quantity, scar tissue, fibroids, etc.

 http://www.resolve.org/about-infertility/medical-conditions/secondary-infertility.html?referrer=https://www.google.com/

I don’t know your history, but have you had many miscarriages or chemical pregnancies? Why is your RE telling you they expect you to have an egg quality issue before they can accurately assess your eggs? I would be very wary of that, unless you have had issues with previous pregnancies and chromosomal problems. As I mentioned before, there is no way to test for egg quality, and there is also no treatment for it, unfortunately. Even if you have had a retrieval and seen your eggs as deemed, “poor quality” (I have), your protocol would be very different than it is currently. There isn’t one exact thing that can change your quality, but there are slight modifications that research supports in terms of trying to increase the quality rather than inhibit it.

Post # 487
Member
1129 posts
Bumble bee
  • Wedding: July 2013

BeverlyGeese :  I have had one miscarriage but that’s all. I was confused when my amh came back so good and asked her why the discordance between the two. She said best guess egg quality but there is no definitive way to tell without seeing the eggs. So I guess we will know relatively soon if that’s what we are dealing with !

Post # 488
Member
2420 posts
Buzzing bee
  • Wedding: April 2014

YogaMama :  Well, your doctor either misspoke and meant to say egg quantity, or she is needing a refresher course on what FSH actually can predict LOL. There is a slight coorelation between egg quality and egg quantity, without a doubt. But despite my high FSH (15), low AMH (0.1) and low AFC (2-4 total), my RE absolutely would not just toss around the term poor quality. She said that until we observe the eggs after retrieval, we assume they are of good quality (even though I had 2 miscarriages prior to IVF) and that our protocol was based on FSH levels.

Post # 489
Member
1129 posts
Bumble bee
  • Wedding: July 2013

BeverlyGeese :  mine did say my age is on my side and that was the best predictor.  I honestly think the borderline fsh threw her off when taken into account with my other test results.

Post # 490
Member
2420 posts
Buzzing bee
  • Wedding: April 2014

YogaMama :  Also, after my first retrieval it was deemed that I not only had poor quantity, but poor quality. I had eggs that were atretic (dead, dying, looked black/brown or discolored and irregularly shaped). My protocol for the second retrieval changed to add additional supplements for a short time before starting stims as well as a testosterone based suppressant phase to start building better eggs. 

Post # 492
Member
2420 posts
Buzzing bee
  • Wedding: April 2014

YogaMama :  Sure, your FSH level is borderline at worst (and still considered within semi-normal range just a possible lower response time to stims)…but alone it is not an indicator of anything more than just how you will respond to meds. It shouldn’t have thrown your doctor off at all, in my opinion. You literally can’t diagnose quality without seeing the eggs, and quantity cannot be assessed unless you meet all 3 criteria for DOR (AMH, FSH, and AFC) or low AMH and AFC, plus elevated E2 levels on CD3 (to determine if FSH is suppressed naturally by elevated E2). Like I said, there is a slight coorelation between quality and quantity, but no RE would diagnose that without clear evidence. 

Post # 493
Member
1129 posts
Bumble bee
  • Wedding: July 2013

BeverlyGeese :  Oh I agree with you.  Believe me. I’ve done a lot of research on my own and I’ve had questions.  But I also figured she knows better than I do. Luckily I will have 2 other doctors looking after me from here on out so maybe I’ll get some differing opinions

Post # 494
Member
523 posts
Busy bee

gatordeb :  My first cycle that happened to me on day 2 and the RE (not MY RE) I saw the next morning blew me off. I never felt that way again although I was pretty brain dead/sleepy by the end of my first cycle (fine for my second). If you have to do weeks of IM injections, you will be pregnant and I promise, you won’t care (until the end). So far I can tell you it becomes no big deal and it’s definitely worth it.

Post # 495
Member
341 posts
Helper bee
  • Wedding: July 2015

Wow I missed so much in a few days! Update here- im at 6 weeks 2 days and saw the heartbeat yesterday at the RE (perk of going through IVF is that you get to go for weekly sono and bloodwork so you get to see whats going on before usual!) So far week one was just a black dot- and yesterday was a black dot with two white dots- one of which flickered on and off. cool! Hope everyone is doing well and so happy to see a bunch of new people joining! Good luck to all of you!

gatordeb :  I never felt sick during the stims, just supper uncomfortable to bend and stuff toward the end and cramps after the trigger shot. Hopefully it will pass for you and might not be related. I had a hard time with the PIO intramusculars (if you go back in the thread you can see all my whining lol) but the numbness and pain went away 2 weeks after I stopped. I also dont think my response was normal at all. I have a feeling its bc im thin and didn’t have too much for the needle to go into but idk for sure. Most people are like Dreaming and did fine. If you don’t want to do so many weeks of PIO you could ask to stay on just vaginal suppositories. My RE agreed to let me do that after the numbness issue (think we hit a nerve) and they just monitor your progesterone and said they would put me back on injections if it fell too low. Some people (actually a lot of people) prefer the injections bc really they shouldnt and dont usually hurt, and the suppositories leak out so you have to wear a pad 24/7.  BUT I have a feeling my RE kept me on the PIO as an extra layer of secruity that probably wasnt really needed with the suppositories too. 

BeeBlake :  I’m so excited you got your results back and have two good ones!!! Sorry you missed the boat on this cycle but that’s awesome that you’re gearing up for transfer 🙂

Post # 496
Member
1129 posts
Bumble bee
  • Wedding: July 2013

bellarose606 :  congratulations! Enjoy seeing that little bean every time!

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