IVF – when did you know you needed a second round?

posted 5 months ago in TTC
Post # 2
Member
2107 posts
Buzzing bee
  • Wedding: August 2014

We only knew we’d need a second round when we did a fresh transfer during round 1. None of ours made it to freeze so we had 2 for a fresh transfer so we knew if it didn’t work, it was back to the drawing board. If you are 35 and interested in 2 kids, I’d definitely consider banking. I’ve done 4 rounds and have exactly 3 frozen embryos. Likely not enough for 2 kids but I’m getting older and honestly, just want one baby at this point. We are paying entirely out of pocket (now that coverage has been exhausted) and have already sunk a ton of money into IVF, even with some insurance coverage, so banking is not really on the table for us. Plus, my body is very very over it at this point. I’ve done 4 retrievals and am preparing for my first FET next week. The bee you are referencing had 14 day 2 embryos – which is good, but if grown to day 5 (the preferred day to transfer) will likely not be 14. If your embryos aren’t blastocyst (usually day 5) you will definitely need more like her but if you have blasts, you might want to aim for 2-3 blasts per child.  

Another thing to consider is that if you have insurance coverage, they may not cover banking. Some insurance companies will make you transfer any embryos you have before covering another round. To be honest, your doctor’s goal is to give you a baby. If you are concerned about future fertility, I’d raise that with him but unless specifically discussed, his or her immediate goal is to give you a child *now* not potential children in the future, you know what I mean? 

Post # 4
Member
14948 posts
Honey Beekeeper
  • Wedding: June 2011

We found out as we were on our way to our fresh day 3 transfer and got the call that everything (4 fertilized embryos) had arrested overnight and we had nothing to transfer.  So we did a second round, attempted a fresh day 3 transfer of all 2 low quality embryos, which didnt work and had nothing to freeze.  So we did a third round, and same thing, 2 low quality embryos on day 3 and nothing left to freeze……  So we did a 4th round and got 3 blast this time (new RE).  We transfered 2 and got a positive, but then had a m/c at 9w.  By this time I was 36. We knew wanted more than 1 kid, so we did round 5 to bank.  We got 2 blast and transfered the one from round 4 and one of those, and got a positive, but had a m/c at 5.5w and was left with just 1 embryo again.  So we did a 6th round, which was a complete bust 100% abnormal fertilization, and so there was a 7th round, which resulted in 1 blast and now we had 2 total.  Then I had a lap and ovarian drilling which could possibly improve egg quality… and decided just one more cycle of this madness, an 8th which resulted in 2 more blast.  Now we had 4 total – transfered 1 and it finally resulted in our son.  

I guess that was a really long winded way to say not over think anything right now and take it a day at a time.  Don’t kill yourself trying to plan for this unknown.  It’s good that you’re considering what ifs… but just take it one step at a time.  Let this cycle play out and get some concrete results before you really think about what you have to do.  What you think you may do now, may end up completely different than what you would end up doing when you’re in the thick of it anyways.  (I said I’d never do more than 3 cycles cause if it didnt work after 3, what’s the point??  And look where I ended up…).  You may decide after this round that trying to have a baby now is more important than potentially having 2.  You may decided that another retreival now only sets you back a month or two and it’s worth the insurance to have more to try with.  Heck, for us, we have 3 more embryos now and my husband has asked me if I’m SURE i want another cause he’s not so sure, so maybe all that banking was for nothing in the end and I shouldn’t have bothered.  And you may be lucky to have most your eggs become high quality blasts, who knows!

Post # 6
Member
14948 posts
Honey Beekeeper
  • Wedding: June 2011

goldenbrown :  Slightly.  I started taking a few more supplements, but mostly my first RE kept dropping my stims for fear of OHSS since I have minor PCOS (25+ AF), and my second RE kept it steady (and I did get minor OHSS my 4th cycle).  I also had HGH added with my second RE.

Post # 7
Member
368 posts
Helper bee
  • Wedding: November 2013

So I can’t really answer the question because we thankfully only needed one round of IVF, however, our initial follicle count was 14 and didn’t change. We only retrieved 7 mature follicles of those, 4 fertilized and 2 made it to freeze.  We did PGS testing and only one was a normal embryo.  I am 36 and had hoped to get at least 2 healthy embryos so if we wanted another child we could go back and do a transfer, however that was not meant to be.  The plan we paid for with the fertility clinic did not allow us to do banking, but if it is feesable, I would talk to your doctor about banking, even if you get pregnant from this round of IVF, by the time you could do another retrieval, you will be older and egg quality will be even more depleted.  However, I wouldn’t write off this round, as they say it only takes 1, which ended up being true for us.  I am currently 35 weeks pregnant with our only viable embryo from our IVF cycle!

Post # 8
Member
7919 posts
Bumble Beekeeper

goldenbrown : it all depends on how many embryos you end up with, how many children you want, and how lucky you get with transfers. I ended up with 4 good embryos on day 5 – one was transferred fresh and the other 3 were frozen. That fresh embryo is now a 2 year old little girl! We want to children so we feel our odds are good that one of our remaining frozen embryos will take. Meanwhile I have friends with the same scenario that went through all of the embryos from her first retrieval and then did a second round and then got their child. 

Post # 10
Member
550 posts
Busy bee
  • Wedding: October 2015 - Fairmont Banff Springs Hotel

goldenbrown :  I have had my follicle count change during my cycle both of my 2 retrieval cycles. The first time I strongly suspect I was oversuppressed with the BCP but I started out with 20 follicles in my AFC and the number dropped steadily until they retrieved 5 follicles – 3 mature and 1 5-day embryo. 

For my second cycle, I refused the BCP and primed with estrogen – they started out counting 13 follicles and every day they would give me a higher count in my ultrasounds until they retrieved 23 eggs. So the number can definitely change from your AFC. 

However, I wish I had given more thought to cancelling my first cycle and paying the small fee rather than going through with it. That’s the one thing I have been kicking myself over – I KNEW it didn’t feel right and I wanted to do it again but I went through with it anyways.

Post # 11
Member
2035 posts
Buzzing bee

I did IVF last year at 35, you may not be diagnosed with diminished ovarian reserve because at our age that number of follicles is pretty normal.  Seems like they were usually only measuring around 7-8 follicles for me with 2-3 really looking good.  I was very nervous but we couldn’t really afford a bunch of banking cycles anyway. 9 eggs retrieved, all mature, 6 fertilized, 2 day 5 blasts, one of those is my 5 month old son.  We’ll try the other blast someday but most likely not another IVF round if it doesn’t work.  We were also technically male factor.  

Post # 13
Member
550 posts
Busy bee
  • Wedding: October 2015 - Fairmont Banff Springs Hotel

goldenbrown :  Yeah there was a little push back but when I explained my reasoning they let me do it. I was on BCP for like 50 days on and off and it was way too much. I had a bad feeling when my follicle count kept going down and I really wish I had listened to my gut and postponed my retrieval another month until I had more going on. It was such awaste of money going through with that first retrieval!

I should hear back today or tomorrow on how many day 5 embryos we have to send to testing and I am sooooo nervous. I am trying not to email them for an update because I want the number to be as big as possible and I am worried I will be devastated if it’s small because they are growing the embryos for one more day. 

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