IVF – when did you know you needed a second round?

posted 5 months ago in TTC
Post # 32
Member
310 posts
Helper bee

goldenbrown :  Can you get a second opinion? Or wait until you see the doctor before you start BCP?

I agree, thats so much money to spend on a second cycle if they’re going to do the exact same thing that didn’t work in the first cycle. 

Post # 33
Member
964 posts
Busy bee
  • Wedding: September 2012

goldenbrown :  Repeat IVFer here chiming in with my experience.  I don’t blame you at all for wanting something to change after your failed cycle – and I don’t think increased stims with the same protocol would be enough for me.  We did a typical antagonist cycle for my first round with BCP priming.  It was an epic failure. 1 egg retrieved and a chemical pregnancy.  My RE through that the BCP might have been the problem so we tried estrogen priming with the same antagonist protocol (but with higher amounts of stims).  Another failure – 2 eggs retrieved and a miscarriage at 6 weeks.  For Cycle 3 we went back to BCP priming but changed my protocol to a microdose lupron flare.  Huge difference!  26 eggs retrieved and 4 frozen embryos.

Sometimes our bodies just don’t like one protocol over another and unfortantely, IVF can be a VERY expensive experiment until they find the right combination.  But I would be tempted to push back if they simply want to do the same protocol with more meds.

Post # 34
Member
2033 posts
Buzzing bee

Are there any other clinics near you that you could try if your doctor is resistent to trying something different?  Maybe your doctor knows best, and I’m sure they do want you to succeed but it might be worth at least consulting somewhere else to see if they suggest a different protocol that you trust more.  

Post # 38
Member
964 posts
Busy bee
  • Wedding: September 2012

goldenbrown :  So, out of our 26 eggs, only 6 fertilized.  BUT, we didn’t do ICSI.  We had 100% fertilization on our previous rounds and on the day of retrieval my eggs and my husband’s sperm looked great so we didn’t think ICSI was necessary.  We tried to do rescue ICSI the next day on the remaining 20 eggs and 18 more fertilized. Unfortunately, they arrested just before making it to blastocyst. Had we done ICSI right away, we probably would have had a much higher fertilzation rate and maybe ended up with more embryos.  If we have to do another round, we will try ICSI right away.

Don’t let my results scare you.  My ovaries are VERY resistant to meds so I was on a very high amount of stims for a very long time.  I had to stim with 450 Gonal-F and 150 Menopur for 18 days before we made it to retrieval.  So it’s possible that the amount of stims I had to take compromised my eggs a bit.  The 4 embryos that survived look fantastic so hopefully that means they are the best of the bunch!

Are you taking any supplements for egg quality?  It’s disappointing that you couldn’t get into the July cycle but maybe the extra time on some supplements will help you grow the best eggs possible!

Post # 40
Member
550 posts
Busy bee
  • Wedding: October 2015 - Fairmont Banff Springs Hotel

goldenbrown :  Hey! How are you doing? Did you get in on a July start date? Is this round going better than the last?

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