(Closed) IVF with or without steroids?

posted 4 years ago in TTC
Post # 16
Member
2340 posts
Buzzing bee
  • Wedding: January 2012

I too took steriod for my successful ivf attempts. Like others it was more for immune issues, I can’t remember when I started taking them, but I guess it was a few days maybe before egg retrieval. Not sure it made a difference for egg quality since it’s main aim was for immune issues.

Immune issues are funny though, and I vaguely remember reading one doctor’s opinion that it can affect egg quality that is, if your tnf’s are really high. Might be worth doing some further research on. Good luck with your egg retrieval and FX for a bfp!!! 

Post # 17
Member
5891 posts
Bee Keeper
  • Wedding: October 2010

Only time I was given steriod was for immune issues. I didn’t have any diagnosed issues, but RE figured “what the hell, might as well try it”. But ended up not taking them because all the embryos failed to make it past day 3. So I never took them.  

Post # 18
Member
7310 posts
Busy Beekeeper
  • Wedding: October 2011 - Bed & Breakfast

Steroids are not standard at my clinic. We were treated for MFI, a friend and her husband were unexplained, and another friend and her husband were PCOS. None of us used steroids in our cycles (4 cycles between the 3 of us, all successful).

Post # 20
Member
5891 posts
Bee Keeper
  • Wedding: October 2010

mrsdanish:  Yes, I was supposed to start them either after retrival (in wich case I took a few,I just don’t remember) or after TRANSFER. 

PS- there is adifference between Transfer and Implantation. Transfer is what happens, usually on day 5, when they put the embryo(s) into your uterus. Implantation happened approx 6 days after that when the embryo has fully burrowed into your uterine lining. Implantation doesn’t alway happen. RE’s do not make implantation happen. Implantation is kinda a magical, miracle, unknown. 

I mention this only because the lay media often says a RE implants the embryo which is just wrong. The RE transfers the embryo. Then the waiting (the unbearable waiting) begins to see if the embryo and your uterus want to cooperate and implantation happens. 

Post # 21
Member
854 posts
Busy bee
  • Wedding: May 2013

I’m on my first IVF, and like others, I’m supposed to take steroids for the transfer, but not during stims. Good luck!

Post # 23
Member
2 posts
Wannabee
  • Wedding: June 2013

I took human growth hormone during my 2nd IVF cycle. My protocol was kind of throw every possible drug at my body (DHEA, Co-Q10, testosterone, and estrogen during the month before; Steroids and Human Growth Hormone with the Stims). My RE didn’t think any of these actually helped, but I have DOR and poor response to drugs. She did say that a lot of REs think that it works miracles, so it must work for some people. I think it’s worth a try. I don’t think I had any side effects from it, but it’s hard for me to say because I was taking so many different drugs.

 

Post # 24
Member
2 posts
Wannabee
  • Wedding: June 2013

  I took human growth hormone during my 2nd IVF cycle. My protocol was kind of throw every possible drug at my body (DHEA, Co-Q10, testosterone, and estrogen during the month before; Steroids and Human Growth Hormone with the Stims). My RE didn’t think any of these actually helped, but I have DOR and poor response to drugs. She did say that a lot of REs think that it works miracles, so it must work for some people. I think it’s worth a try. I don’t think I had any side effects from it, but it’s hard for me to say because I was taking so many different drugs.

Post # 25
Member
1819 posts
Buzzing bee

mrsdanish :  I pushed IVF until fall  but from what the nurses explained to me, I believe they mentioned steriods for me as well… which if this is not common I will be questioning this as well.

Post # 28
Member
523 posts
Busy bee

mama2bee71 :  I did two IVF retrievals, a frozen transfer (failed) and a fresh transfer (successful). My RE only uses steroids during fresh transfers- it was a short course and as long as I took it early enough in the day my side effects were minimal (I had trouble falling asleep if I took it too late). I did not use the steroid during my failed frozen transfer. I don’t think it’s rare, just based on RE/clinic decisions. 

The other thing I found interesting was the forms of estrogen used- after my fresh transfer, I used vaginal estrace (until beta). During FET cycle, they had me on the oral form.

Post # 29
Member
1819 posts
Buzzing bee

Dreaming13 :  Thank you for that information. We are going to go with frozen and maybe 1 fresh with the plan we are chosing. The RE was saying frozen has a better chance than fresh so thats why we were going to go with frozen. 

Post # 30
Member
523 posts
Busy bee

mama2bee71 :  My RE said the same however we anticipated a good number of blasts and for the first cycle planned on a fresh transfer. The fresh transfer never happened because I overstimmed and felt like crap. Our blast rate was not what we had anticipated (10% made it to blast). We did a subsequent frozen transfer that failed and were left with one frozen blast. I had surgery to repair a uterine septum and then did another IVF retrieval cycle. Anticipating a better outcome than the first cycle, I opted again for the fresh transfer. On day 5, I had 1 great looking blast and 9 still growing (most looking good). I felt great. It was a successful transfer BUT only 1/9 made it to the freezer (10% blast rate, no clinic issues). There is something wrong with our sperm/eggs/something when they combine that causes an issue at the cellular level. I’m really glad I did the fresh transfer, having to go through the prep of a frozen transfer isn’t terrible but it’s always a crapshoot. Now I’m pregnant (11 weeks) and I have 2 chromosomally normal frozen embryos.

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