Progesterone Compound, Prometrium Questions

posted 3 years ago in TTC
Post # 2
Member
4134 posts
Honey bee
  • Wedding: August 2013

Prometrium comes in a capsule and can be taken orally or vaginally (I took it orally). It is more easily absorbed vaginally so if you have a severely low progesterone number, it is usually suggested you do vaginal as it works better. I’ve never heard of prometrium being a compound, but I’m sure there is such a thing. 

You can start taking it now, but it may not help as much as when you take it starting after O. Can’t hurt, just may not help as much. 

Also, progesterone supplements generally delay AF from showing up until you stop the supplements. My OB told me to stop taking the prometrium at 16DPO (I was temping and confirming my O date) if I didn’t get a BFP by then. 

I now have 2 healthy kiddos, a 2.5 year old and a 9 month old thanks to prometrium 🙂 

Post # 3
Member
776 posts
Busy bee

ilovethesun :  that sounds right to me. I havelow progesterone and supplement with it vaginally twice per day starting 3 DPO. I know you can take it orally too but I’ve read that the vaginal supplement work better. Since your 4dpo I’d start immediately. As the PP mentioned, it does delay AF so if you normally have a short LP and you don’t get your period don’t get too excited until you get a bfp. Fingers crossed for you bee!!

Post # 4
Member
2420 posts
Buzzing bee
  • Wedding: April 2014

ilovethesun :  crinone is the compounded form of vaginal progesterone. Prometrium typically comes in 200mg capsules, as the pp has said, that you can take orally or insert vaginally. There are a lot of forms of progesterone so I would make sure you ask the pharmacist which is being prescribed and how to take it. Endometerin is also a vaginal suppository but it is a hard, larger pill that is inserted with an applicator. 

I was always told to take it 3 days post ovulation until 14dpo, test and stop then if negative because it will most likely delay your period (although not uncommon to spot on it if the cycle was unsuccessful).

Post # 6
Member
4134 posts
Honey bee
  • Wedding: August 2013

My typical LP was 10-11 days so a 16dpo was unheard of for me. And the OB said if I were pregnant, I’d get a bfp by then so to stop. Since you have had a 16 day LP, maybe stop 18dpo or so? BUt I’d think you’d get a bfp by 16dpo if you were pregnant that cycle. 

Post # 9
Member
776 posts
Busy bee

ilovethesun :  Hmm, I’m not 100% sure if it would make a difference or not at this point. If you are pregnant though progesterone is an essential component in maintaing a pregnancy so I don’t think it would hurt to go ahead and start it at 9DPO. BeverlyGeese  is so experienced with this stuff so maybe she’d have better advice 🙂

Post # 10
Member
2420 posts
Buzzing bee
  • Wedding: April 2014

ilovethesun :  So, progesterone is responsible for encouraging growth of your uterine lining so the fertilized egg can implant and obtain nutrients vital for development. It can’t hurt to take it starting at 9dpo, but if your progesterone was low it’s possible that your lining already wouldn’t be able to accept a viable embryo due to lacking thickness/nutrients etc. Basically, your corpus luteum is responsible for making these hormones before the placenta takes over around 10 weeks. If you have a weak ovulation, often causing low progesterone, then you would be put on a supplement if pregnancy does haopeb to occur. The additional support, even if this cycle is unsuccessful, or for the 4-5 days you would take it, can’t hurt in my opinion.

Post # 11
Member
2420 posts
Buzzing bee
  • Wedding: April 2014

Also, I disagree about stopping progesterone past 16dpo. The window for implantation is very short, as I mentioned above. Your lining has to be receptive to the fertilized egg and it is very, very uncommon for implantation to occur past 12dpo. By 14dpo you should be getting a faint positive if pregnancy has occured. Staying on the progesterone past this won’t do anything except delay your period and cause a longer cycle.

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