(Closed) Recurrent Early Miscarriage/Chemical Pregnancy

posted 6 years ago in TTC
Post # 16
Member
2787 posts
Sugar bee
  • Wedding: June 2011

lastlastfirst: I’m really sorry for your losses. I think I’m the OP another bee mentioned. I’ve had 4 confirmed consecutive chemical pregnancies, and I’m almost sure I had a fifth one. We are currently on our 10th cycle TTC, so it has been a painful TTC journey. My first OB didn’t want to do any testing even after I had 3 chemical pregnancies, so I decided to switch doctors and my new OB ordered tons of testing, push to have an RPL (recurrent pregnancy loss), it’s a panel of blood tests (clotting and immunological issues). Also ask your doctor to do a CD3 baseline test (FSH, LH, E2) and AMH (this can be tested any day of your cycle) . Wishing you all the best and hoping you get your sticky BFP soon

Post # 17
Member
1019 posts
Bumble bee
  • Wedding: August 2014

Did you have any complications with your egg donation and I’m assuming you’ve let your current doctors know that you did this in the past? Research is slowly starting to show that egg donation can come with more long-term risks than once believed, including permanent complications from ovarian hyperstimulation syndrome and permanent hormone disruptions. Unfortunately as eggs are treated like a commodity carrying high price tags, fertility clinics can be overzealous in their administration of drugs that stimulate ovary production in donors. So just in case you didn’t think to mention it, do let your doctor know. 

Sorry you’re going through this 🙁 

Post # 18
Member
21 posts
Newbee
  • Wedding: September 2015

lastlastfirst:  I’m sorry to hear about your losses! One thing to have the doctor look into: anti-phospholipid antibody syndrome… This should be considered in anyone with 3+ miscarriages. Take care and good luck. 

Post # 21
Member
1019 posts
Bumble bee
  • Wedding: August 2014

lastlastfirst:  okaaaaaay, good to hear…was just a suggestion. 

Post # 22
Member
2787 posts
Sugar bee
  • Wedding: June 2011

lastlastfirst: Thank you for being an egg donor and helping families achieve their dreams to have children 🙂 ……There is something I just thought about, ask your OB for karyotype testing for your husband (DNA translocations), if you had 6 successful donor cycles, you don’t have any translocations. Darling Husband and I were both tested as part of the recurrent pregnancy loss panel of tests. By the way most of the tests mentioned in this thread are included in the RPL. When I had mine, they got 18 tubes of blood to send to different labs.

Post # 23
Member
113 posts
Blushing bee

lastlastfirst:  I had 2 chemical pregnancies in the first 5 months I was charting and TTC.   My practitioner put me on Clomid and now I’m pregnant (22 DPO…).  I’m obviously still nervous, but I think it’s going to stick. It just FEELS different. I’m not sure if Clomid was the difference, but I’ve heard that a “stronger” ovulation can do the trick for some women. 

I’ll be thinking of you in the months to come and hope you get answers, and a sticky pregnancy. 

Post # 24
Member
1009 posts
Bumble bee
  • Wedding: June 2012

 

lastlastfirst:  That’s awesome that you donated.  I did IVF, so I did the stims for egg retrieval, and am currently almost 17w pregnant so I doubt that’s an issue.  Do you know if any of the donations resulted in pregnancies/live births?  That could tell you something about egg quality.  Have they run tests on your Darling Husband to look into his sperm quality?  I can’t remember names of the various tests (my Darling Husband didn’t have enough sperm to test), sorry.  There was a Bee who graduated from the 1+ board a while back (I’m an alum of that board too, and echo the above suggestions– those ladies are the reason I was sane with all we went through) who had I think 6 early losses before she got her sticky bean.  She had some sort of septum (embryos would implant on the septum, leading to early loss), and hormone/genetic issues.  I’m assuming your’ve already had an HSG and saline ultrasound?  She also had the MTHFR mutation and progesterone issues.  It was once the septum was finally removed (one doc didn’t remove it completely) and she was on PIO injections that she finally made it to the point that she saw a heartbeat.  Wishing you the best of luck!

Post # 27
Member
1009 posts
Bumble bee
  • Wedding: June 2012

That’s great that you’ll be taking letrozole.  I was found to have an issue with implantation, and my RE said that for 65% of women with those issues, letrozole takes care of the problem.  So that’s really good that you’ve got that base covered.

 

Post # 28
Member
7430 posts
Busy Beekeeper
  • Wedding: February 2013

My best friend has this problem. She has no problem getting pregnant, just staying pregnant. She had three miscarriages before having her son. She has to take progesterone and an experimental drug called lovenox I believe. She has a 2 year old, and is pregnant right now with her second. She had one miscarriage between the two pregnancies I think. 

Post # 29
Member
1617 posts
Bumble bee
  • Wedding: October 2014 - Cape May

I can tell you there is hope. My Future Sister-In-Law miscarried Sept of 2012 and had trouble conceiving since. She went for routine monitoring and no cause was found ever. She is now 6 months along, due weeks before our wedding and doing well! It took a ton of dr visits and several specialists but she is doing great ( considered extremely high risk so she has to check in 2x a week with the hospital). There is hope! I remember how devastating it was the first time and each time after to see her suffer. A good doctor and careful monitoring maybe all you need. Feel free to search until you find someone that can delve into the situation and hopefully give a good game plan to follow. 

Post # 30
Member
6 posts
Newbee
  • Wedding: October 2012

Im so sorry for all of your losses. I would request to have your progestrone checked now while your not preg. I have low progestrone and have been TTC for 19 months. I just had my second clyle of Clomid to try to raise my levels and my Dr. is having me start progestrone supositories after ovulation. He said to take them from Ovulation til I start my period. If I get a BFP to continue to take them til after the first trimester. 

Progestrone levels are a comon cause to miscarriages. I dont think it will hurst to be put on the supositories from the begining. Good luck!

 

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