TTC with Metformin – but the nausea!

posted 4 months ago in TTC
Post # 2
Member
407 posts
Helper bee

I was on metformin for about two weeks and gave up because of the side effects. I had no side effects on clomid

Post # 3
Member
7462 posts
Busy Beekeeper

selenanana :  how quickly did you ramp up your dose? I took it without side effects but I had at least a week at each level to acclimate. I had bad side effects with clomid though. 

Post # 5
Member
7462 posts
Busy Beekeeper

selenanana :  I just re-read your original post. Honestly with a history of PCOS and 2 years without a successful pregnancy I would move on to a reproductive endocronologist and get their opinion. OBs specialize in patients that are already pregnant – not patients who are trying and failing to become pregnant. The RE might suggest something other than clomid. However my side effects with clomid were bad in that I was hyper emotional for the duration of the medication. A short small price to pay if it works in my view. Has your husband been tested? Just because you have PCOS doesn’t mean he can’t also have an issue. 

Post # 7
Member
7462 posts
Busy Beekeeper

selenanana :  I did not get pregnant on clomid. I took it as part of an IUI cycle which our doctors didn’t even recommend – they wanted us to go straight to IVF but I was nervous and asked to at least try the IUI before breaking out the big guns. I did get pregnant on my first try with IVF though.

Are you going to be without insurance for long? I just mention it because the bill for my unmedicated vaginal birth (in which I barely made it to the hospital on time and was already pushing while they were wheeling me into the delivery room where my kid popped out 19 minutes later) was about $10k to my insurance. And that doesn’t even cover the post-partum ward! 

Post # 8
Hostess
9602 posts
Buzzing Beekeeper
  • Wedding: March 2014 - Chicago, IL

selenanana :  Have you tried the extended release version? It’s easier on the GI tract.

Post # 9
Hostess
9602 posts
Buzzing Beekeeper
  • Wedding: March 2014 - Chicago, IL

selenanana :  Also I just read that you’re tapering up 500 a week. Go slower. 500 for 2 weeks, take before bed with some food. Then increase to 1000 for 2-3 weeks, always taking with food. Then up to 1500, again, always with food.

Post # 11
Member
248 posts
Helper bee
  • Wedding: October 2015

I have PCOS and am just on the metformin to keep my cycles regular and control weight.   I had to switch to almond milk and cut back on dairy and that helped with nausea and gastro side effects. I can do yogurt periodically and cheese with no issues..it’s the plain milk, cottage cheese or things like milkshakes that get me or sauces with cream. My doc also has me taking my pills with lunch and dinner and not at breakfast as they seem to limit stomach upset taking them after a main meal. My other tip is large carbohydrate filled meals or those high in fat do not agree with the metformin for me so I limit those splurges. It will pass I promise. I just have to watch what I’ve found to be my trigger foods. 

Post # 12
Member
17 posts
Newbee

Take it just before you go to bed and sleep through the nausea! The XR version also helps. I have been on metformin for 15 years. Good luck!

Post # 13
Member
113 posts
Blushing bee
  • Wedding: November 2020 - North Carolina

I’m on Metformin (500 mg) twice a day for my diabetes. OMG I feel your pain. It’s best to eat something first. So I take it with my biggest meals. My doctor told me that it was best to slowly get up to my recommended dose. So I was only taking half a pill per day for 3 days, then 2 halves for three days, then a pill and a half, etc… She also said that if I started feeling the side effects real bad then to go back down to the previous dose. So if I was taking 2 pills to go back down to a pill and a half. But I don’t know anything about PCOS so I’m not sure if slowly dosing yourself is even an option. Good luck!

Post # 14
Member
2626 posts
Sugar bee
  • Wedding: December 2017

selenanana :  Clomid isn’t very effective in people with PCOS. Femara/letrozole is the medication that is more effective for those of us with PCOS.I think a fertility specialist would be a great person to start seeing, since you’re at 2 years of trying. Are you taking the metformin with food? Maybe you need to eat some ginger or something with it? I guess I didn’t really have that side effect; only the diarrhea at times depending on what I ate. At first though, because I had heard about the side effects, I took it at night and then went to sleep. 

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