(Closed) What is it like taking Estrace? (FET)

posted 4 years ago in TTC
Post # 3
2427 posts
Buzzing bee
  • Wedding: April 2014

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weightwatchers152 :  Sorry you haven’t gotten any replies on here yet. I haven’t taken it orally and I am sort of a strange duck as the suppository form doens’t really do much for me. I also took it in combination with patches, and then in combination with both patches and IM injections – so I can’t honestly say how it made me feel. I could definitely tell a difference on days when i changed my patches and took an IM injection.

The pills are tiny, and I honestly found it easier to just wash my hands and insert that way. When I started taking endometerin, I did put the estrace in the same applicator as the endo pill and inserted that way. They are messy, so you will want to have plenty of liners (also because they are blue). We joked that my cm was the color of cotton candy or like I had sex with a smurf. (IVF humor..ha)

I also started taking estrace on CD3, but it did make me bleed heavier than I had been the first two days. It’s just a little bit extra messy but since you are taking it orally as well, you should still have the effect of the meds and once AF ends it will seem much less gross to insert. Since I took 2mg/3x a day, my nurse said just to space them out as evenly as you can (so when I woke up, 8 hours later, and before bed). I will recommend that if you can, to wake up a few hours earlier than normal (I would get up at 5 when my husband woke up for the day) and then I would sleep for a few more hours. It cut down on the mess for sure.

Good luck – feel free to PM me if you have any other questions. Sorry my experience isn’t the same and I just wanted to make sure someone responded as best as could.

Post # 4
1915 posts
Buzzing bee
  • Wedding: August 2013 - backyard in the woods

Personally, I set my alarm and took it at the same time every day. I wasn’t told to do so, I’m just neurotic like that. I had no issues putting it in or with it staying in, period or no. The tiny pill basically sticks inside you once it’s in. I just used my fingers. You might get a little blue discharge- this is normal. What your body doesn’t need will just leak out. I always took mine internally, because when I tried switching to taking it orally it made me very sick. Nausea and diarrhea. My RE suggested I switch back to internal estradiol and my sickness stopped right away. I am very sensitive to hormoes FYI, this is not typical, but not uncommon either. I also took my prometrium and my estradiol internally at the same times and had no issues doing so.

Post # 5
771 posts
Busy bee
  • Wedding: May 2014

I have to take mine vaginally and I take it and my Prometrium when I go to bed so it will stay where it is intended.

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